Case Study

Comparing the Effects of Binder Type on Tablet Compression Properties

Source: Metrics Contract Services

By Anshul Gupte, Michael Dehart, and Rahul Haware

The purpose of the present investigation was to compare the impact of roller compaction processing parameters and resulting tableting properties of roller compacted granules of Avicel ® DG (ADG) [Spray Dried-­‐Co-­‐processed Microcrystalline Cellulose], physical mixture of Avicel ® 101 (75%) and Anhydrous Di-­‐calcium Phosphate) (25%)] (PADCP), and Co-­‐Povidone [Kollidon ® VA-­‐64 Fine] (KVA64).

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