Determining Filter Cake Resistance And Its Pressure Dependence

Slow filtration is typically due to particle properties such as highly anisotropic particles, a compressible filter cake, or particle attrition. Build-up can lead to subsequent batches filtering poorly, leading to manufacturing delays and process inefficiency.

Manipulating your particle habit during crystallization through a solvent switch or temperature cycling can help to optimize crystal shape, resulting in improved filtering speed. Review an instance of poor filtration and learn how to determine optimal filter cake resistance and compressibility.