Determining Performance Improvements in NovaPure® Plungers for Syringes in Autoinjector Systems

NovaPure^® 1-3 mL plungers were developed with the Quality-by-Design (QbD) method for use in pre-filled syringes - especially those coupled with autoinjectors. Present work is a 1-year study examining performance with placebos of different viscosities 1, 8, 15 cps) in a laboratory configuration that replicates an autoinjector. Parameters evaluated are delivery time, delivery volume, and initiation/sustaining force legacy comparison is FluroTec^® ART 2345 1-3 mL plunger.

Benefits of a Pre-Filled Syringe Autoinjector System

• Fewer steps in usage (no need to withdraw product from a vial)
• Better delivery accuracy
• More efficient use (vials can not be emptied completely)
• Fewer/eliminated visits to hospital/clinic visits (lower costs)
• More convenience - easier compliance with patient lifestyle
• Better safety - needle is automatically ejected and withdrawn (and shielded from view, reduced patient anxiety)
• Better compliance through connectivity with smartphone apps