Poster

Determining Performance Improvements in NovaPure® Plungers for Syringes in Autoinjector Systems

By A. Kim, L. Ho, W. Xu, K. Falcone, T. Haarlander, P. McAndrew

NovaPure® 1-3 mL plungers were developed with the Quality-by-Design (QbD) method for use in pre-filled syringes - especially those coupled with autoinjectors. Present work is a 1-year study examining performance with placebos of different viscosities 1, 8, 15 cps) in a laboratory configuration that replicates an autoinjector. Parameters evaluated are delivery time, delivery volume, and initiation/sustaining force legacy comparison is FluroTec® ART 2345 1-3 mL plunger.

Benefits of a Pre-Filled Syringe Autoinjector System

  • Fewer steps in usage (no need to withdraw product from a vial)
  • Better delivery accuracy
  • More efficient use (vials can not be emptied completely)
  • Fewer/eliminated visits to hospital/clinic visits (lower costs)
  • More convenience - easier compliance with patient lifestyle
  • Better safety - needle is automatically ejected and withdrawn (and shielded from view, reduced patient anxiety)
  • Better compliance through connectivity with smartphone apps

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