Article | August 5, 2021

Developing A Robust In Vitro Intestinal Model For Preclinical Candidate Screening Of GI Toxicity

gastro intestine digestion stomach iStock-1265549997

Gastrointestinal (GI) issues are common side effects of many drugs. Anticipating such side effects before clinical trials is limited by a lack of effective models for evaluating preclinical candidates for their potential to cause diarrhea, nausea, and other gut-related side effects. With its RepliGut® in vitro human intestinal model, Altis Biosystems is developing a system that could help pharma companies identify GI toxicity issues early in the drug development process.

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