Development Of An Aseptic Transfer System

As the pharmaceutical industry began to move to smaller microenvironments in which to perform manipulations and sterile transfers, the need was created for isolators and RABs which provide barrier containment and aseptic conditions and has since created the need to reduce the footprint within manufacturing facilities again. This also allows for smaller batch transfers and contract manufacturing options.

ChargePoint developed the Bio valve to overcome this challenge, where the valve itself provides the safe transfer conditions in a sealed environment, eliminating the requirement for large area high grade cleanrooms surrounding the process.

The decontamination of the Bio valve chamber is a twostep sterilization process. This article discusses the options available for the sterilization process in the current market and the results that drove the design of the Bio valve the industry knows today.