Dry Granulation Systems
If a tablet press is used for the compaction process, the term slugging is used. But since particles with a small particle size do not flow well into the die of a tablet press, the results are weight differences from one tablet (slug) to another.
If a tablet press is used for the compaction process, the term slugging is used. But since particles with a small particle size do not flow well into the die of a tablet press, the results are weight differences from one tablet (slug) to another. This in turn causes large fluctuations in the forces applied onto the individual slugs, with translates in variations of the slug’s mechanical strength. Therefore, the properties of these granulates obtained by milling the slugs cannot be controlled well either. This is one of the main reasons why slugging is hardly used any more as a dry granulation method.
Roller Compaction
A GERTEIS® Roller compactor generally consist of three major units:
- A feeding system, which conveys the powder to the compaction area between the rolls
- A compaction unit, where powder is compacted between two counter rotating rolls to a ribbon by applying a force
- A size reduction unit, for milling the ribbons to the desired particle size