Product/Service

Formulation Development Solutions

Source: Aragen
Research laboratory microscope-GettyImages-1564542843

Accelerate your drug development with our comprehensive pre-formulation, formulation, and novel delivery system expertise, tailored to optimize physical form, enhance solubility, and support scale-up.

Pre-Formulation Development

Physical form selection

  • Crystallisation
  • Salt screening
  • Co-crystal screening
  • Polymorph screening

Oral delivery

  • Suspension
  • Solution
  • Microemulsion
  • Solid dispersion
  • Nanosuspension

Parenteral delivery

  • Solution
  • Suspension
  • Liposomes
  • Microparticles
  • In-situ gels

Topical delivery

  • Lotion
  • Gel
  • Cream
  • Ointment

Nasal delivery

  • Solution
  • Suspension
  • Emulsion
  • Dry powders

Preclinical studies Support

  • Efficacy studies
  • PK studies
  • Exploratory tox studies
  • GLP tox studies

Formulation Development and Manufacturing

Tablets

  • Immediate Release
  • Sustained Release
  • Mini
  • Bilayer
  • Delayed Release
  • Colon delivery
  • Oral films

Liquids

  • Suspension
  • Solution
  • Emulsion

Parenterals

  • Solution
  • Suspension
  • Lyophilised
  • Ophthalmic
  • Nebulised
  • Vial/Ampule/
  • Pre-filled Syringe

Capsules

  • Powder
  • Pellets
  • Liquids

Semisolids

  • Gel
  • Cream
  • Ointment
  • Lotion

Processes/Technologies

  • Wet Granulation
  • Roller Compaction
  • Micronisation
  • Nanomilling
  • Spray Drying
  • Fluid Bed Coating
  • Tabletting
  • Capsule Filling
  • Film coating
  • Packaging

Novel Drug Delivery System Development (Oral)

Solid Dispersion

For poorly soluble compounds to increase dissolution rate and saturation solubility amorphous drug within a polymer

Microemulsion

Avoid influence of solid form. Increase solubility in GI tract. Compound is completely solubilized

Nanosuspension

For poorly soluble compounds to increase dissolution rate and saturation solubility crystals in nano size range

Novel Drug Delivery System Development (Parenteral)

Parentera

Targeted drug delivery system

Microemulsion

Long-acting Injectable microspheres using biodegradable polymers

In Situ Gels

Controlled release of drug using thermo-sensitive polymer gels