Article | July 29, 2020

Freeze Drying Of Vaccines – Challenges And Concepts In Formulation And Process Development

By Julia Kosan, Ph.D candidate, Friedrich Alexander University, Erlangen, Germany

cold thermometer cold chain temperature controll

Vaccination prevents millions of deaths from infectious diseases per year; however, there are still millions of people who die from these diseases due to weak thermostability demanding cold chains, long-term stability issues and distribution challenges. All these limitations can be overcome by creating a dry product through lyophilization. With the urgency to develop a coronavirus vaccine, it is a crucial time to discuss the process of freeze-drying vaccines.

Recently, Ms. Julia Kosan, a PhD candidate from Friedrich Alexander University, Erlangen, Germany presented a webinar that discussed the suitability of freeze-drying vaccines to increase their thermostability. This article summarizes the webinar and includes a selection of questions from the Q&A session.

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