From Powder To Robust Tablet With Less Material: Compaction Simulator Arrives At Ardena Ghent

By Laure Descamps

Modern pharmaceutical development requires accelerating solid oral dosage programs while minimizing active pharmaceutical ingredient consumption. Advanced compaction simulation technology allows scientists to predict formulation behavior on production presses using only minimal quantities of raw material. By evaluating compressibility, compactibility, and tabletability from the earliest development batches, researchers can make data-driven go or no-go decisions well before large-scale manufacturing begins. This methodology replaces traditional trial-and-error bench methods with deep process insight, identifying potential risks like capping, lamination, or lubrication issues early. Furthermore, modular platforms support specialized formats including multi-layer configurations and dry granulation screening, significantly streamlining the path to clinical manufacturing.

Discover how advanced compaction simulation can optimize your formulation timelines by exploring the full overview.