Fundamentals Of Particle Size Analysis

Micronization, the process of reducing active pharmaceutical ingredient (API) particles to the micrometer scale, is vital for numerous pharmaceutical applications, as the quality and performance of these particles hinge on precise characterization. Accurate particle size analysis is critical across all phases of drug development, from early research to commercial production, ensuring the success and efficacy of pharmaceutical products. While some drug developers invest in costly equipment or build in-house expertise, many are increasingly outsourcing analytical testing to achieve precise, consistent, and efficient results.

Outsourcing to experienced contract development and manufacturing organizations (CDMOs) offers a streamlined and cost-effective approach to particle size analysis. With specialized equipment and expertise, these partners enable pharmaceutical companies to enhance their analytical capabilities without the burden of additional infrastructure. This article explores the importance of particle size characterization and the advanced analytical techniques employed to assess micronized particles effectively.