Headspace Measurement Services

GettyImages-157291618 Scientist inspecting vial

Headspace measurement services are carried out by LIGHTHOUSE laboratory facilities in Charlottesville, Virginia and Amsterdam, The Netherlands. Clients requiring rapid non-destructive headspace analysis can choose from several service options. Samples can be sent to LIGHTHOUSE for analysis, equipment can be brought to the client and analysis performed on-site by LIGHTHOUSE Application Scientists, or equipment can be implemented at the client on a project basis for a short-term lease. Headspace systems from LIGHTHOUSE utilize a patented laser absorption technique developed with funding from the Food and Drug Administration and have been implemented & validated by the industry for more than a decade. Measurement Services clients take advantage of the expertise at LIGHTHOUSE gained from analyzing millions of samples from sterile drug facilities all over the world to address the following applications:

Applications include:

  • Container closure integrity inspection and leak rate modeling
  • Headspace oxygen stability studies
  • Nitrogen purge optimization & validation
  • Lyo chamber moisture mapping
  • Lyo cycle optimization
  • Packaging permeation studies
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