Case Study

How A Placebo Formulation Is Designed For An Oral Solid Dose Product

Source: Metrics Contract Services

By Thomas B. Gold and Allen Lawson

OBJECTIVE

To demonstrate the process by which a placebo formulation was designed for an oral solid dose product that would be dispensed to the patient as a fast-dissolve tablet.  The tablet is added to water and the resulting solution is dosed as a antibiotic mouthwash.   Placebo matching was required not only for the tablet but also for the solution which the patient took.

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