Article

How Can Extrusion Benefit Your Pharmaceutical Oral Drug Product?

Source: AbbVie

By Bei Chen, AbbVie

iStock-185955499-lab-cleanroom

Extrusion processing is intended to continuously manufacture (for continuous manufacture of) homogeneous and structured products. Due to its immense adaptability, extrusion has been widely utilized in diverse fields. It is being adopted more recently by the pharmaceutical industry at an unprecedented pace to address various drug product formulation and manufacturing needs. The twin screw extrusion process can be used to not only manufacture novel drug delivery systems via thermal or ambient temperature processing, but also to replace batch granulation processes. During extrusion, powder blend(s) or a granular mix is often compacted and converted into product of defined shape and density by forcing it through an orifice or die under controlled conditions. Compared to a traditional batch process, this exciting yet complex technology offers may advantages including but not limited to higher manufacturing efficiency and excellent product uniformity.

VIEW THE ARTICLE!
Signing up provides unlimited access to:
Signing up provides unlimited access to:
  • Trend and Leadership Articles
  • Case Studies
  • Extensive Product Database
  • Premium Content
HELLO. PLEASE LOG IN. X

Not yet a member of Pharmaceutical Online? Register today.

ACCOUNT SIGN UP X
Please fill in your account details
Login Information
ACCOUNT SIGN UP

Subscriptions

Sign up for the newsletter that brings you the industry's latest news, technologies, trends and products.

You might also want to: