XD® Technology: Improve Biopharmaceutical Production

A Revolution for Mammalian Cell Culture Processes

XD® Technology is a reveloution in process technology, pushing the cell density in mammalian systems to the max to drive yield improvements in the production of biopharmaceuticals.

DSM's XD® Technology has been developed to drive yield improvements in the production of biopharmaceuticals. XD is able to push the cell density within the bioreactor to the max and thereby achieve maximum productivity. XD's ultrahigh yields allow for downsizing of bioreactors and opened avenues for new biopharmaceutical manufacturing concepts.

DSM's patented XD technology works in a continuous media feeding mode, with a filtration unit to retain both the cells and the recombinant protein in the bioreactor. The constant nutrient supply and the removal of potentially toxic metabolites result in a more optimal environment for the cells to grow and to reach higher cell densities.

DSM's patented XD® technology works in a continuous media feeding mode, with a filtration unit to retain both the cells and the recombinant protein in the bioreactor. The constant nutrient supply and the removal of potentially toxic metabolites result in a more optimal environment for the cells to grow and to reach higher cell densities.