Article | April 16, 2025

Innovations In Biopharmaceutical Equipment: Shedding Light On Oligonucleotide Manufacturing

By Steve Foy, manager, products and brand strategy at Asahi Kasei Bioprocess

GettyImages-1349793348 DNA

As demand skyrockets for oligonucleotide therapeutics – drugs that precisely target genetic material to treat complex diseases – the spotlight turns to manufacturing efficiency and scalability. Producing these complex molecules reliably and cost-effectively requires specialized equipment. Innovations like automated solid-phase synthesizers offering seamless scaling, dedicated cleavage and deprotection systems enhancing safety, and specialized tangential flow filtration systems for optimal purification are crucial.

These advancements are key to overcoming production bottlenecks and realizing the full potential of oligonucleotide medicine. Explore the specific technologies revolutionizing oligonucleotide manufacturing by reading the full article.

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