Q&A

Insight From An Expert: A Chemist's Secrets To Efficient API Scale-Up

By Evan Boswell, Senior Principal Scientist, Pfizer CentreOne Contract Manufacturing

Insight From An Expert: A Chemist’s Secrets To Efficient API Scale-Up

The “recipe” for manufacturing an active pharmaceutical ingredient (API) usually evolves during the journey from flask to commercial manufacture. As you scale up, the efficiency of your API synthesis becomes increasingly important. In the end, the goal is to have a viable process that produces the same results day after day, creating a reliable, cost-effective supply chain for your drug product. For smaller pharmaceutical companies, an efficient process can also provide a “sweetener” for attracting a Big Pharma buyer.

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