Product/Service

Intellipharm PK

Source: Intellipharm, LLC

Intellipharm PK is a software program developed for Windows that simulates drug plasma concentrations based on drug physical and pharmacokinetic parameters.
Intellipharm PK is a software program developed for Windows that simulates drug plasma concentrations based on drug physical and pharmacokinetic parameters. The software also provides the following output:

  • Percent of dose absorbed as a function of time
  • Amount of solid (undissolved) drug in the GI tract as a function of time
  • Amount of dissolved drug in the GI tract as function of time
  • Initial drug particle size distribution

All output is in the form of text files that can be easily graphed using Microsoft Excel.

The software provides guidance in selecting drugs that will have a better chance of surviving development hurdles. Through simulation, selection criteria for drug properties can be established. When improvement in drug properties is needed, the magnitude of improvement can be gauged to decide whether to use synthetic or formulation modification. The software will also sharpen one's insight into how various parameters affect the performance of a drug.

For scientists involved in formulation design and quality control, the software can be used to provide guidance in setting particle size specifications to ensure consistent dissolution and absorption.

Intellipharm PK has been developed based on published research.

Intellipharm, LLC, PO Box 644, Niantic, CT 06357-0644. Tel: 860-691-0142; Fax: 860-739-4261.