Liquid Filled And Sealed Hard Gelatin Capsules

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The hard gelatin capsule has been conventionally used as a dosage form for Rx and OTC drugs and herbal products, which are formulated either as powder or pellets. Various categories of drugs, however, demand new and different ways of formulation and the market demands that these products are developed and launched in an ever decreasing time period.

This article will review how liquids filled into hard gelatin capsules can fulfill some of these demands and in particular will review the categories of drugs for which the liquid and semi-solid filled capsule is particularly relevant, examine the compatibility issues associated with excipients, compare the liquid filled and sealed hard gelatin capsule with soft gelatin capsules and also describe a new process for sealing hard gelatin capsules.

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•White Paper: Liquid Filled And Sealed Hard Gelatin Capsules