Method Selection Suite™: Develop Chromatographic Methods Faster With Prediction And Optimization Software
Your Method Development Toolbox
ACD/Method Selection Suite is your software assistant for LC and GC method development. When you want to develop methods using Quality by Design (QbD) principles, and make every experiment count, reach for Method Selection Suite to:
- Choose your starting conditions and columns
- Simulate separations under new conditions
- Optimize your chromatography with 1D, 2D, or 3D models
- Predict the retention times of new compounds
- Database successful methods for future use
Benefits
Have More Confidence in Your Development Process
Start development with well-chosen conditions
- Choose a pH, solvent, and temperature that makes sense for your compound by predicting pKa, LogD, boiling point, and more.
Screen a full set of columns
- Explore a range of chemistries by using the Column Selector to pick orthogonal columns and find the most effective retention mechanism.
Optimize methods with fewer experiments
- Minimize experiments by using simulation to determine how the chromatogram would look under different conditions.
- Find the optima in a few clicks.
Produce 3D models that fit reality
- Optimize in 1D, 2D, or 3D.
- Ensure the model fits your experiments by customizing the modelling equations.
Increase chances of method robustness
- Get better chances of passing robustness tests by starting with a rational approach and visually understanding your design space.
How it Works
Rational, Reproducible Steps
- 1Predict the physicochemical properties of your compounds (pKa, logD, boiling point, and more). Use that information to select starting conditions.
- 2Choose columns to screen with the Column Selector.
- 3Run some initial experiments with the conditions above.
- 4Use this initial data to model your separation.
- 5Find the best conditions for your method.
Product Features
Features of Method Selection Suite
- Physicochemical Property Prediction
- Column Selection
- Data Import and Processing
- Modelling and Optimization
- Databasing and Reporting
- Multi-Technique Processing
More Reasons to Use Method Selection Suite
Why Take a Software-Assisted Approach to Method Development?
Method development by trial and error can result in many wasted experiments. (And it’s incompatible with QbD principles.) By taking a rational approach, you can be confident of getting a good separation in a reasonable time, and justify your approach to others.
Software helps you with a logical approach by predicting physicochemical properties, calculating modelling equations, and optimizing. It also helps you share your results through shared databases, so your entire team can understand your project.