By Chris Rombach, ILC Dover
Two methods of containing blenders have been demonstrated. Included here are the use of flexible enclosures and separate, disposable powder transfer systems.
The systems described in this containment guide center around bin blending and v-Blender applications in Oral Solids Dosage (OSD) manufacturing using Flexible enclosures. Blending involves the controlled mixing of dry primary powder particles and excipients. The powders can range in proper- ties and potency and, if not contained, can present cleaning and exposure issues.