Brochure | September 24, 2018

Micro-Dosing And Powder-In-Capsule Evaluations

Source: CapsugelĀ® | Lonza Pharma & Biotech
Powder

Micro-dosing is the process of dispensing a precise amount of drug substance into a capsule or bottle for use in early phase human studies. Lonza’s Xcelodose® Precision Powder Micro-Dosing systems and market-leading experience in micro-dosing enable premier powder-in-capsule (PIC) evaluations and services for your preclinical studies. We can help you accelerate initial studies to determine if the drug substance should receive further investment — which is critical for cost-effective product development.

Extensive capability and capacity

Micro-dosing for PIC evaluations is a key component of our early stage product development offering aimed at optimized product design and speed to clinic. PIC programs are generally completed approximately 50% faster than traditional formulation development approaches — resulting in savings of up to 6 months to first-in-human studies. Our Xcelodose® equipment can accommodate a wide range of powders, including blends and highly potent compounds, in doses as low as 100 micrograms.

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