Application Note

Application Note: Micro-Formulation For Intravenous Injection

Source: Cirrus Pharmaceuticals, Inc.
The purpose of this work was to develop methodologies for formulating new chemical entities (NCEs) for intravenous injection using only a few milligrams of the NCE. This "micro-formulation" approach was developed to facilitate in vivo screening of drug candidates at an early stage of development, when many NCEs may be under consideration and very little of each may be available. Submitted by Cirrus Pharmaceuticals