Modern Containment Solutions In OSD Processes
By Scott Patterson

There’s a changing landscape in the containment world for OSD processing. While previously there was master site planning for an extended period, we now have very short-range production planning, and we follow a lot of the CMO model for multiple-use products in a facility. Original containment strategy was focused on operator exposure, and while we still focus on operator exposure today, we also concentrate on mitigating risk for cross contamination. Also now with global manufacturing sites, we see smaller batch sizes and more changeover, which require greater levels of efficacy, efficiency, and speed.
In this paper we consider the pros and cons between a hard-wall system and a flexible-wall containment systems.
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