Modified-Release Formulation Strategies

The popularity of modified-release (MR) dosage forms continues to rise due to the many therapeutic benefits that they offer for both drug developers and patients. Compared to immediate-release (IR) formulations, MR dosage forms can offer maintenance of drug plasma concentrations over a prolonged period and drug delivery to targeted regions of the GI tract for localized treatment, among other benefits.

While there are many benefits to oral MR formulations, there are also several challenges in developing them, including ensuring that the formulation can withstand changes in environmental conditions. This brochure will explore these benefits and challenges, as well as the different MR formulation technologies that are available.