mRNA Process And Cost Modeling: A Tool To Optimize Process Development

The COVID-19 pandemic brought into focus the impact that mRNA technology can have on rapid drug development. mRNA is an attractive modality to work with because of its relative simplicity compared to other biologics; it is wholly synthetic and does not require cellular materials.

Demand for mRNA-based medicine production in lower income countries continues to increase, as do investments in prophylactic and therapeutic indications, such as infectious diseases and cancer.

Explore a cost-model that compares all vaccine modalities, such as virus-like particles, viral vectors, and mRNA. This cost modeling approach enables decision making on production scale and plant sizing. In addition to several aspects of the cost-model, learn about ways to meet forecasted mRNA demand.