Explore the mRNA universe with Cytiva. In this series, Cytiva scientists share their journey and insights on mRNA synthesis for research purposes and they share their advice on how to scale.
In vitro transcription (IVT) is the synthesis of RNA molecules, allowing a researcher to tailor synthesis and introduce modifications to produce a transcript. It’s worthwhile to spend some time optimizing mRNA template design, IVT, and other process parameters to simplify downstream processing and ensure the appropriate balance of yield and secondary structure formation.
Learn more about IVT along with process challenges and strategies.