Neotame And Sucralose: Two Ways To Ace The Taste Test

Bitter APIs can undermine the palatability of oral medications, particularly for pediatric and geriatric patients. Neotame and sucralose offer clean, sugar-like taste profiles alongside the stability and formulation flexibility needed to address this challenge. Neotame delivers 8,000 to 13,000 times the sweetness of sucrose, providing strong cost efficiency and heat stability at low use levels. Sucralose combines effective taste masking with ready solubility and aqueous heat and pH stability. Powder and granular forms support the distinct processing needs of solid and liquid dosage forms. Both sweeteners can also be used in oral films, lozenges, effervescent tablets, and orally disintegrating tablets.

Gain insight into performance comparisons, recommended applications, dosage guidance, and regulatory documentation designed to support excipient selection and streamline formulation decisions.