NovaPure® Syringe Plungers eBook: Chapter 3: Syringe Performance

The effectiveness of a pharmaceutical product depends heavily on the mechanical integrity of its containment system. For prefilled syringes and autoinjectors, injection performance is measured by precise variables: the volume of drug delivered, the duration of the injection, and the force required to initiate movement. If these components fail to meet strict tolerances, patient safety is compromised, and sterility requirements—such as those defined in EU GMP Annex 1—are at risk.

Advanced plunger components are engineered to maintain a secure Container Closure Integrity (CCI) while ensuring consistent functionality. By minimizing initiation forces and resisting atmospheric pressure changes during transport, these components provide the reliability necessary for self-administration. Understanding these performance parameters is essential for mitigating drug containment risks.