Application Note: Optimization of Solvent Drying ProMaxion for Dryer End-Point Detection

The vast majority of pharmaceutical intermediates and end products are produced by synthesis, which requires a combination of chemicals, a solvent into which they are mixed, and a reaction process to produce the desired pharmaceutical. The chemicals may be purchased in bulk or manufactured at another part of the plant on site. A common solvent is isopropyl alcohol (IPA), but the pharmaceu-tical industry uses a vast range of solvents including xylene, methyl bromide, methyl chloride, dimethyl acetamide, and many more. The reaction process includes some combination of heat, cooling and agitation to cause the product to precipitate out of the mix. At the end of this, the chemical stage, the product is laden with solvent which must be extracted before moving to the finishing phase (intermedi-ates) or consumer packaging (end products).