Oral Solid Dosage Products: Water Activity And Primary Packaging Selection

Primary packaging for oral solid dosage (OSD) products is designed to protect the product and slow the rate of moisture uptake over time. Every individual OSD product has a different starting water activity. It’s essential to measure the initial water activity point of freshly packaged products, as well as over time, because water activity content can change from batch to batch, drug to drug and ingredient to ingredient. Being able to monitor the water activity content quickly, effectively and precisely over time allows you to assess the different primary packaging options suitable for your oral solid dosage product.

This short video explains more about USP <922> water activity and primary packaging selection of oral solid dosage products.