Parteck® MXP: Two Polymers, Unparalleled Value

Introducing Parteck® MXP, a groundbreaking range of polyvinyl alcohol (PVA) excipients meticulously engineered for hot melt extrusion (HME) applications. Parteck® MXP enhances drug solubility and bioavailability through a solvent-free process that is both effective and environmentally sustainable. With two specialized grades—Parteck® MXP 3-82 and Parteck® MXP 4-88—these products are designed to optimize HME performance to ensure stability of active pharmaceutical ingredients (APIs) across a broad temperature spectrum.

Parteck® MXP 3-82 features a lower degree of hydrolysis which enables superior interaction with hydrophobic drugs and acts as a potent precipitation inhibitor. On the other hand, Parteck® MXP 4-88 has a higher hydrolysis grade that excels in stabilizing amorphous forms of challenging compounds. Both grades are compliant with the European Pharmacopoeia and supported by the comprehensive Emprove® Program, which facilitates regulatory compliance through extensive documentation. These innovative excipients not only enhance solubility—demonstrating remarkable increases for drugs like Atorvastatin and Itraconazole—but also offer flexibility for various downstream processing methods.

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