Newsletter | September 17, 2025

09.17.25 -- Pathway To Approval: Analytical Strategies To Support GLP-1 Receptor Agonist Development

Understanding Biotherapeutic Peptides And GLP-1 Receptor Agonists

Biotherapeutic peptides represent a promising class of therapeutics that offer significant advantages over traditional small-molecule drugs, particularly in terms of safety and efficacy. Learn why rigorous impurity profiling is vital to ensure product quality and regulatory compliance.

 

Challenges In The Development And Production Of GLP-1 Receptor Agonists

GLP-1 receptor agonists are transforming the landscape of modern therapeutics, extending far beyond their original role in managing type 2 diabetes. These peptide-based drugs are now being explored for a wide range of applications. Explore analytical innovations that ensure safety and efficacy as these peptides expand into multiple treatments.

 

Advancements And Challenges In GLP-1 Peptide Drugs

Unpack the rapidly evolving landscape of GLP-1 therapeutics—an area gaining momentum for its potential in treating metabolic disorders such as diabetes and obesity—with expert Matt Lauber to gain insight into GLP-1 therapeutics, analytical challenges, and the innovations shaping the future of biopharmaceuticals.

 

Method Development Considerations For The Manufacturing Of GLP-1 Analogs

The role of synthetic peptides in drug development is rapidly expanding, driven by their versatility and ability to target specific biological pathways with high precision. Discover how advanced RP chromatography methods are vital for impurity profiling to ensure safety and efficacy.

 

Development Of Separation Methods For GLP-1 Synthetic Peptides

A novel analytical approach utilizing HPLC coupled with UV and mass spectrometry (HPLC-UV/MS) has been developed to enhance the characterization of GLP-1 analogs. Uncover how this method analyzes GLP-1 analogs to address critical challenges in peptide separation, impurity detection, and performance for improved reproducibility.

 

SOLUTIONS

GLP-1 Receptor Agonist Solutions

Waters offers comprehensive workflow solutions that streamline every stage of GLP-1 receptor agonist development—from characterization to purification—helping accelerate the delivery of safe therapies.

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