Application Note

Performance Of Novapure® Plungers For Syringes In Autoinjector Systems

By Amy A. Kim, Le Ho, Tara Haarlander, T. Page McAndrew, West Pharmaceutical Services, Inc.

West-NovaPure

An important element of drug product lifecycle management is anticipating use of delivery systems. When moving from vial systems to pre-filled syringes and autoinjector systems, factors to consider include patient and caregiver needs, drug product requirements, system components, and performance. This article presents performance of West’s 1-3mL and 1mL Long NovaPure® plungers versus legacy plungers for pre-filled syringes in autoinjectors; both plungers are formulation 4023/50 Gray. Performance of the NovaPure® plungers was equivalent to or better than legacy plunger performance in all aspects. Coupled with the enhanced features of NovaPure® plungers, this work indicates they are suitable when best performance is needed.

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West Pharmaceutical Services, Inc.