Performance Starts With Better Delivery

Better delivery is more than a dosage form. It’s how we partner with our customers to bring their molecule to market.

We work with biotech and pharmaceutical companies on complex, often low‑solubility molecules, combining softgel and lipid-based delivery to solve their bioavailability and solubility challenges.

From early development through to commercial supply, our teams work alongside yours, with direct access to the experts doing the work and the hands-on experience to solve the challenges that come with complex molecules.

We are a proven supplier of pharmaceutical softgels to the U.S. market, with a strong track record supporting regulated products from development through launch.

Focused on softgels

Every softgel program brings complexity. Its success comes down to focus.

Our structure is designed to keep you close to the science, with direct access to senior experts and decision-makers. Fewer handoffs, clearer communication, and tighter alignment mean your program progresses efficiently at every stage.

Focused, expert-led teams
Deep softgel and lipid formulation expertise
Agile execution across the full development lifecycle

Softgel and lipid-based expertise for complex molecules

Douglas CDMO specialises in softgel and lipid-based formulation for lipophilic and poorly soluble APIs, including high-potency molecules.

From early fit assessment through to scale-up and commercial readiness, our scientists work directly with your team to develop formulations designed for performance, stability, and regulatory success.

Delivery capabilities

Our capabilities span the full softgel development and supply lifecycle:

Lipid-based formulation expertise

• Solving solubility and bioavailability challenges for complex molecules
• End-to-end development
  From pre-formulation and early clinical supply through to commercial readiness
• Analytical and stability support
  Methods and studies tailored to lipid-based systems
• Scale-up and tech transfer
  Robust, predictable progression from development to PPQ
• Commercial supply and lifecycle management
  Reliable manufacturing with ongoing optimisation

Why consider softgels for complex APIs

Softgel dosage forms offer a proven approach to improving performance for lipophilic and poorly soluble molecules, enabling more effective delivery of APIs that would otherwise be limited by solubility and absorption challenges. Key benefits include:

• Improved bioavailability
  Lipid-based fills enhance absorption and consistency
• Enhanced stability
  Sealed shells protect against air and moisture
• Patient-friendly format
  Easy to swallow and widely preferred
• Safer handling
  Reduced exposure during manufacture supports potent compounds