Pharmaceutical Micronization

Micronization is the process of reducing the particle size of liquid pharmaceutical products using dynamic high pressure homogenization, to make a dispersion of the active ingredients much more stable for enhanced clinical effectiveness.

The bioavailability of active pharmaceutical ingredients in the product prepared for medical dosing is improved with optimized particle micronization and homogeneous distribution. This means improved tolerance of drugs on patients with calibrated and reduced dosage.

Any fluid pharmaceutical dispersion or emulsion, in a wide range of product viscosities, can also be easily homogenized in a single pass under aseptic conditions by using cGPMvalidated high pressure homogenizers manufactured with FDA approved wetted parts. Premixed products enter the GEA NiroSoavimicronizer with 500 micron maximum size broad particle distribution, and after the high pressure treatment the large particles are dispersed and reduced down to the range of nanometers depending on the application. High pressure homogenization can also be applied to recombined nutritional products with optimized formulation and to sub-micron intravenous emulsions.

Our competence in pharmaceutical applications can give you technological support for dynamic high pressure homogenization on

•  Antibiotics
• Ingredients
• Ointments
• Medicinal syrups
• Syrups
• Vitamins
• Enzymes
• Nutritional products
• Gels
• Intravenous emulsions
• Vaccines
• Inhalation products
• liposomes