Application Note

Advantages Of Preparing Wet Granulations In A Planetary Mixer

Source: Charles Ross and Son Company

Planetary mixers are ideal for wet granulation processes. Advantages include "one-pot" processing, high uniformity and yield, predictable performance, and ease of cleaning.

Process validation required by the Food and Drug Administration is intrinsically easier to accomplish using a “one-pot” method for granulation as can be achieved in a planetary mixer, rather than the “multiple-pot” approach that is needed for other mixers. For example, the PowerMix’s planetary stirring and high speed chopping action is capable of carrying out all phases of the wet granulation procedure including