PreVUE™ System
The system combines the strength of two proven USFilter technologies--CDI-LX™ continuous electrodeionization system and full fit polyamide reverse osmosis membranes--into a single packaged system. USFilter has installed more than 2,000 CDI systems with over one-third in validated pharmaceutical applications.
The system is hot water sanitizable at 85 degrees C to enhance microbiological control and is integrated through a central control system that is designed to comply with 21 CFR Part 11.
The skidded system includes a pretreatment step, which softens and filters the feedwater reducing hardness and suspended solids. A break tank simplifies operation by self-regulating pressure to the reverse osmosis unit, recycles waste streams, and eliminates the need for further equipment for chemical sanitization. The reverse osmosis and CDI-LX™ systems are the core of the PreVUE system providing consistent, high quality USP water without the use of chemicals.
The PreVUE system features
- cGMP design and construction
- Comprehensive validation and documentation per GAMP 4 standards
- Latest PLC technology for optimum process security
- Full-fit RO membranes for reduced biological contamination
- Continuous electrodeionization for reliable operation
- Fully functional, wet Factory Acceptance Test, complete with loaded membranes to demonstrate both performance and efficacy of the sanitization cycle.