ProSim Simulated Moving Bed

Process description
The separation processes by preparative chromatography provide possibilities to separate with a very high yield multi-components mixtures in which the components have various adsorption affinities. Potential applications are in agrochemicals, food, pharmaceutical industry, fine chemistry.... In these industries, the traditional separation processes (absorption, distillation column, liquid-liquid extraction,..) must be turned down because of the substances thermal stability or for economic reasons. Consequently, separation by chromatographic way appears to be competitive for very high purity separation, for delicate products with close chemical structures (isomer, enantiomers..) and even for relatively significant tonnages as in sugar industry (glucose, fructose…). In these techniques, the components separate because of their difference in propagation velocity in the liquid-solid medium.

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