Product/Service

Protein Formulations and Analytical Services

Source: Cirrus Pharmaceuticals, Inc.
Cirrus' scientific staff has the expertise and instrumentation to carry out full development programs for protein-based or derived pharmaceuticals. Capabilities include peptide or protein characterization, stability evaluation, formulation, and process development of molecules as sterile liquids and lyophilized cakes for parenteral and alternative delivery routes.

Click Here To Download:
•Product Sheet: Peptides and Proteins: Macromolecular Therapeutics
•Product Sheet: Physical and Chemical Characterization
•Product Sheet: Analytical Capabilities

Our scientific staff has the expertise and instrumentation to carry out full development programs for protein-based or derived pharmaceuticals. Capabilities include peptide or protein characterization, stability evaluation, formulation and process development of molecules as sterile liquids and lyophilized cakes for parenteral and alternative delivery routes. Our biotechnology team has the combined expertise to tackle all aspects of development and the experience to surmount the unique challenges of working with macromolecular drugs.

Backed by a talented analytical group, our peptide and protein product development team is prepared to address all aspects of product development, including:

  • Degradation studies
  • Formulation development
  • Assessing stability of drug in formulation
  • Sterile filtration process development
  • Container/closure selection
  • Manufacturing process development
  • Terminal sterilization
  • Lyophilization
  • Drug product stability testing
  • Scale-up and technical transfer
Chemical Stability is typically assessed by studying degradation rates, degradation pathways, identifying degradation products and by generating pH-rate profiles. Physical Stability is typically assessed through studying aggregation, unfolding/denaturation, adsorption and interaction with surfaces. pH-solubility profiles are usually generated to provide information about compound solubility during the formulation development process.

Click Here To Download:
•Product Sheet: Peptides and Proteins: Macromolecular Therapeutics
•Product Sheet: Physical and Chemical Characterization
•Product Sheet: Analytical Capabilities