Proving The Design Space: Advancing The Development Of Syringe-Device Combinations

By Enrico Barichello and Courtney Nicholas Sutton

Reducing injection frequency means higher concentrations, and higher concentrations strain what an autoinjector can deliver. Injection time, cap removal force, dimensional fit and silicone-related stability all pull against one another, and the integration task has traditionally fallen to the drug developer. This article from Enrico Barichello (Product Manager, Syringe Platform, Stevanato Group) and Courtney Nicholas Sutton (Head of Portfolio Strategy, SHL Medical) makes the case for defining the design space in advance. It describes a compatibility study run under simulated storage, use and drop conditions, using placebo formulations from 1 cP to 50 cP, and considers what such data means for platform selection across a pipeline.

Explore the test design and results to see how supplier collaboration can shape the path from investigational drug to approved product.