Article: Pseudoempirical Modeling Ensures Effective Drug Packaging

By Adrian Possumato, Global Director Healthcare Packaging, Multisorb Technologies

Packaging conditions are an important factor in ensuring the safety and potency of a product throughout its shelf life. However, performing tests to identify the ideal packaging requirements can be complex. Without a strategic approach to drug packaging and testing, there can be delays in bringing a new product to market.

Fortunately, there are proven, streamlined techniques to predict how a particular drug will fare in a given package. While stability testing will ultimately determine whether formulation and packaging development decisions were made correctly, pseudoempirical modeling of established drug product formulations with desired packaging presentations can help drug makers quickly determine the means by which they can maintain a drug's chemical and physical characteristics over time. Pseudoempirical modeling can be used in advance of stability testing of solidstate pharmaceutical degradation and sorbent technology in drug packaging.