Video

Rapid Non-Destructive Product Moisture Determination In Stability Studies

Dry pharmaceutical product needs to be protected from moisture to achieve an optimal efficacy and shelf life. The motivation for this industry study, was to determine whether Karl-Fischer (KF) titration can be replaced by rapid, non-destructive lyo product moisture determination method. The investigation required evaluation of the correlation between headspace water vapor pressure and the actual degradation of hydrolytic small molecule API.

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