Real-Life Application Of Intensified Chromatography – See The Results

This study evaluates the impact and benefits of using multi-column chromatography. The Resolute® BioSMB multi-column chromatography system was utilized to demonstrate improvements in productivity and efficiency compared to batch chromatography. Product quality consistency and the potential cost and resin savings of transitioning from batch to continuous were taken into consideration. A goal of the study was to execute the process transfer and scale up as quickly as possible. Performance data showed product yield and quality to be consistent throughout the 150× scale-up of the process and comparable to the batch benchmark. Continue reading to learn more about the study outcomes.