Application Note

Recommended Mixing Equipment For Medical Adhesives

Source: Charles Ross and Son Company

The growing demand for prescription and over-the-counter transdermal products encompasses a wide range of uses and conditions, from motion sickness and smoking cessation, to hormone replacements and pain management.

At the heart of a transdermal patch manufacturing process are two important mixing steps: preparation of the pressure sensitive adhesive, and preparation of the drug-adhesive solution consisting of the active pharmaceutical ingredient, the adhesive, enhancers/excipients and solvent.

Proper mixing is critical to achieving consistent homogeneity, predictable viscosity and accurate drug content.