Resorbable Delivery™ Polymers
New Drug Delivery, Bioresorbable Polymers
Foster Pharma introduces Resorbable Delivery™ polymers, a new platform for precise drug delivery in a solid structure that can be implanted into the body and is designed to resorb over time.
Resorbable Delivery™ polymer formulations incorporate an active pharmaceutical ingredient (API) into a bioresorbable polymer matrix that can be extruded into fiber or film, or injection molded to meet specific application requirements. Examples include custom formulations using a poly lactic acid (PLA) polymer matrix and analgesic for orthopedic and cardiovascular applications. Medical device and pharmaceutical companies can tailor the polymer and active pharmaceutical ingredient (API) to meet their specific application requirements.
Suitable polymers for this platform include PLLA, PDLA, PLGA, PGA and PCL. These polymers offer biocompatibility, are sterilizable by irradiation or ETO and are absorbed into the body and metabolized. Formulations can be tailored to have degradation times from 1 month to more than 24 months with a tensile strength from 20 MPa to 100 MPa and elongations up to 100 percent.
Foster Pharma's custom Resorbable Delivery™ formulations are manufactured in a Class 7 pharmaceutical clean room using advanced melt extrusion technologies to ensure dispersion of the active ingredient throughout the polymer matrix. Foster also offers extrusion technologies to produce fibers, rods or films. More complex configurations of implants can be achieved through various molding technologies.
"The convergence between pharmaceuticals and devices has been on the rise in recent years through combination products; however, the increasing acceptance of bioresorbable polymers and recognition of their unique ability to provide a structural implant for a limited time, particularly in orthopaedic and cardiovascular markets, has produced the ideal vehicle for drug delivery," says Dan Lazas, President of Foster Pharma.
Foster Pharma is a developer and manufacturer of custom biomaterials for pharmaceutical, nutritional and combination therapy products. Leveraging expertise in melt extrusion technology in a cGMP clean room environment, Foster Pharma is able to support the most critical applications in oral and implantable applications. For more information about Resorbable Delivery™ polymers or Foster Pharma, please call 860-928-4102 or visit www.fostercorporation.com.