Roller Compactor Applications
Dry granulation is used for increasing the bulk density of powders, whilst increasing the particle size, resulting in better flowing material, which is a prerequisite for manufacturing capsules and tablets on high speed production equipment.
Improving Flow Ability
Dry granulation is used for increasing the bulk density of powders, whilst increasing the particle size, resulting in better flowing material, which is a prerequisite for manufacturing capsules and tablets on high speed production equipment. Furthermore, bonding the particles of various substances together during the compaction process reduces the tendency to segregation of powder particles of different substances. This results in an improvement of the homogeneity of the active ingredients (API) within the powder blend, causing an improvement of dose uniformity of such dosage forms.
Wet- & Dry Granulation
In contrast to wet granulation, dry granulation is a continuous process. This results in various economical advantages. Nowadays the throughput of common dry granulation systems can reach 400kg/h. Dry granulation systems require comparatively fewer investments into buildings or equipment. Coupled with lower maintenance costs, this results in a much higher overall profit. Thanks to countless innovations nearly 100% of all dry powders can be processed on GERTEIS® dry granulation systems.
Further Advantages of Dry Granulation:
- Minimal floor space
- Large throughput of material (highly efficient process)
- Continuous process
- Highly energy efficient; no heat for drying and no air conditioning required as for other granulation techniques
- Ultra High Containment Options are available to avoid contamination of manufacturing areas and personal by high potent actives
- Low running costs