Article | July 28, 2025

Saving Costs Without Cutting Corners: Seal Replacement As A Cost Avoidance Strategy

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Ensuring cost savings in biopharmaceutical manufacturing typically involves careful consideration of potential risks to product quality, process integrity, or regulatory compliance. However, this article highlights an exception: the proactive replacement of worn or degraded seals in synthesis columns. This seemingly minor operational investment can prevent significant financial setbacks due to failures, downtime, or batch loss.

Explore how a proactive seal management program can deliver a strong return on investment (ROI) by comparing the cost of seal replacement to the much higher costs associated with contamination events. You will also learn how Artificial Intelligence (AI) can further enhance seal management, shifting it from a reactive task to a predictive, data-driven strategy for even greater efficiency and cost avoidance.

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