Selecting Sterile API Transfer Technologies

The Ritedose Corporation are a North American CDMO producing sterile unit dose products. They were looking to solve the issue of charging sterile drug substance into a mixing tank. This is a widespread problem in aseptic processing and particularly in formulation.

It was vital that sterile conditions were maintained whilst docking a container to the vessel and then transferring solid drug substance to form a liquid suspension. With a fully dissolved liquid, the product could typically be sterile filtered as it was passed to the filler. Although in this case, the product being passed to the filler was a suspension and so this option was not possible.

Read how ChargePoint Technology presented its AseptiSafe Bio Valve as a solution to meet the challenge facing Ritedose due to its unique ability to provide a sealed powder transfer within a small footprint, by being mounted to the inlet port of the vessel.