Solid Form Services

With an estimated 90% of organic molecules exhibiting multiple forms (polymorphs and pseudopolymorphs), the selection of a lead solid form is a critical early step in pharmaceutical development. Solid form selection involves both the chemical makeup of the solid to be manufactured as well as its crystal structure. Both the chemical and physical form determine a range of critical parameters, i.e. manufacturability, stability and bioavailability. These properties impact the development and manufacturing of both the drug substance and drug product.

At Lonza Solid Form Services, we have defined work flows to assess and select solid forms in a cost and time efficient manner that meets the needs of each individual program.