Article | June 5, 2025

Strengthen Pharmaceutical Supply Chains With A U.S.-Based CDMO

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Supply chain disruptions are an ongoing challenge for manufacturers across industries, but pharmaceutical companies can take proactive steps to mitigate these risks — particularly by partnering with an experienced contract development and manufacturing organization (CDMO). A trusted CDMO brings more than just production capacity; it offers a strategic, collaborative approach to supply chain resilience.

Central to this resilience is a robust, well-managed network of raw material suppliers, each rigorously vetted for quality standards, technical responsiveness, and reliability. An established CDMO enhances this network through long-term, strategic partnerships — fostering collaboration that extends beyond order fulfillment. These relationships often involve sharing critical technical information, such as synthesis routes, impurity profiles, and analytical methodologies. This level of integration enables faster, more effective responses to supply shortages, including the identification of alternative sources and the development of new production pathways that can improve material purity and performance.

A U.S.-based CDMO adds another layer of security by prioritizing domestic sourcing where possible, ensuring consistent access to key raw materials, specialty chemicals, and solvents. Moreover, investment in vertical integration—especially for regulatory starting materials (RSMs) and intermediates — further strengthens control over supply reliability and quality. Even when global sourcing is required, working with a CDMO that owns and operates its manufacturing assets ensures greater transparency, oversight, and responsiveness across the supply chain.

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